https://doi.org/10.31288/oftalmolzh201442328

Investigation of the optical properties of the lens (according to the instrument «Manual Straylight Meters») and visual acuity in patients with primary senile cataract receiving the drug bioflavonoid — quercetin

Leus N. F., Girzheva A. V., Zhuravok Y A.

State Institution The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine, Odessa, (Ukraine)

Key words: primary senile cataract, lens, light scattering, quercetin, lipoflavon

Introduction. Urgency of the work is determined by elucidating the actions of bioflavonoid — quercetin in the treatment of primary senile cataract. Purpose. To examine the optical properties of the lens and visual acuity in patients with primary senile cataract in the initial form receiving the drug bioflavonoid (quercetin)

Methods. Patients participating in this study were divided into two groups. The main group was composed of 45patients with primary senile cataract treated with Lipoflavon instillation and oral quercetin, and a comparison group of 43patients with primary senile cataract who did not receive Lipoflavon and quercetin. Eye scattered light was measured in patients with age-related cataract. 

Results. The results indicate that the drug helps slow the development of quercetin and severity of lens opacities in patients with primary senile cataract. This effect is observed after treatment and occurs throughout the follow-up period of 24 months. Visual acuity at 12, 18 and 24 months of the follow-up in the study group was significantly higher in relation to the comparison group by 6.4, 10.7and 15.5 %, respectively.

Conclusions. The application of quercetin in patients with primary senile cataract leads to a distinct stabilization of existing lens opacities, reducing the intensity of light scattering.

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