https://doi.org/10.31288/oftalmolzh201468994

Ultrastructural changes of the rabbits retina after threshold laser radiation with a wavelength of 532 nm, 577nm and 810 nm

N. E. Dumbrova, N. I. Molchanyuk, T. A. Romanova, N. M. Gavronskaya

SI «The Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine»; Odessa (Ukraine)

Key words: ultrastructural changes of rabbit retinal of the outer and inner layers, threshold laser action.

In this article studied the ultrastructural changes of rabbit retinal neuroepithelial after exposure to lasers of different wavelengths. Laser photocoagulation remains the «gold» standard of care for retinal vascular disease. Under active study of the effects of laser energy at different wavelengths on the retina, the search for alterna¬tive methods of dosing of laser energy, as well as the search for optimal laser scars schemes applying to the affected area of the retina. The aim of the work was to study the effect of the threshold laser action on rabbit retinal ultrastructure of the outer and inner layers lasers generating radiation with a wavelength of 532 nm, 577 nm and 810 nm by electron microscopy. Work performed on 5 adult rabbits (10 eyes) Chinchilla, age 6 or 7 months, weighing 2.5—3 kg. Laser scars apply in the lower segments of the eyes, which were divided arbitrarily into two parts to perform the confluent and not confluent laser photocoagulation, using laser radiation of different wavelengths. Laser effect on the rabbit retina was performed in millipulse mode laser used laser power threshold effects. Power laser exposure was adjusted until a visible white scar 1—2 degrees. Control was retina intact rabbits. Found that in the midst of the threshold laser action occurs irreversible destruction of photoreceptor cells after all types of laser exposure. Least damaging effect on the bipolar ganglion cells and Muller has a laser wavelength of 810 nm as compared with the laser wavelength 577 nm and 532 nm when used in a threshold mode.

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