Oftalmol Zh.2014;6:128-131
https://doi.org/10.31288/oftalmolzh20146128131
The case of treatment of the patient with transsudative detachment of the retinal pigment epithelium in age-related macula degeneration
A. Nevskaya, A. R. Korol
State linstitution «The Filatov Institute of Eye Diseases and Tissue Therapy of National Medical Academy of Ukraine»; (Odessa, Ukraine)
Key words: age-related macular degeneration, retinal pigment epithelium detachment, triamcinolone acetonide.
Introduction: serous retinal pigment epithelium (RPE) detachment is an one manifestation of age-related macular degeneration. There is no effective treatment of serous RPE detachment.
Objective: to present the case of treatment of patient with serous RPE detachment associated with age-related macular degeneration by the application of subtenon triamcinolone acetonide.
Material and Methods: vizometry, ophthalmoscopy, fluorescein angiography, optical coherence tomography.
Results There was performed single subtenon injection of triamcinolone acetonide. There was observed complete reattachment of the RPE layer. Recurrence of RPE detachment was not observed.
Conclusion: monotherapy with subtenon injection of triamcinolone acetonide may be applied for treatment of patients with serous RPE detachment associated with age-related macular degeneration
References
1.Katsnelson LA, Forofonova TI, Bunin AYa. Vascular diseas¬es of the eye. Moscow; 1990. 126- 137.
2.Pasyechnikova N. V., Korol A. R. Clinical classification and tactics of management of patients with age related macular degeneration. Oftalmol Zh. 2010;2:38-41. Russian.
3.Agurto-Riveira R, Diaz-Rubio J, Torres-Bernal L, Macky TA et al. Intravitreal triamcinolone with transpu¬pillary therapy for subfoveal choroidal neovascularization in the age-related macular degeneration. A randomized controlled pilot study. BMC Ophthalmol. 2005;25:27.
4.Bird AC. Doyne Lecture. Pathogenesis of retinal pigment epithelial detachment in the elderly; the relevance of Bruch's membrane change. Eye. 1991;5:1-12.
5.Chaudhary V, Mao A, Hooper PL, Sheidow TG. Triamcionolone acetonide as adjunctive treatment to verte-porfin in neovascular age-related macular degenera¬tion: a prospective randomized trial. Ophthalmology.2007;114:2183-9.
6.Decker W. L. Retinal pigment epithelial tears / W. L. Decker, G. E. Sanborn, M. Ridley [et al.] // Ophthalmology. — 1983. — Vol. 90. — P. 507- 512.
7.Pasyechnikova NV, Naumenko VA, Korol AR at al. Serous Pigment Epithelium Detachment Associated with Age-Related Macular Degeneration: A Possible Treatment Approach. Medical Hypothesis, Discovery & Innovation Ophthalmology Journal 2012;1(4):73-6.
8.Hoskin A, Bird AC, Sehmi K. Tears of detached retinal pigment epithelium. Br. J. Ophthalmol. 1981;65:417- 22.
9.Inoue M, Takeda K, Morita K et al. Vitreous concentration of triamcinolone acetonide in human eyes after intravitreal or subtenon injection / M. Inoue// Am. J. Ophthalmol.2004;138:1046-8.
10.Moorfields macular study group. Retinal pigment epithe¬lial detachments in the elderly:a controlled trial of argon laser photocoagulation. Br. J. Ophthalmol. 1982;66:1-16.