https://doi.org/10.31288/oftalmolzh201438993

Ultrastructural changes of optic nerve in experimental model of eye contusion in rabbits

N. E. Dumbrova, T. A. Krasnovid, V. V. Vit, N. I. Molchanuk, N. P. Grubnik

State Institution The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine, Odessa, (Ukraine)

Key words: optic nerve, contusion of the eyeball, ultrastructural changes

Introduction: Direct and indirect injuries can lead to decrease of visual acuity in the eye or head traumas.

Purpose: To study ultrastructure of the optic nerve of rabbits after experimental mild contusion.

Material and methods: We examined 20 eyes. Electron microscopy of the op¬tic nerve was made after experimental mild eye contusion in 1 week, 1 month, 2 months.

Results: Postcontusional disorders were found in neurofilaments, neurotubules, axonal mitochondria.

Conclusion: Early and first ultrastructural changes of the optic nerve were found in experimental mild eye contusion in 1 week, 1 month, 2 months. The main disor¬ders were found in neurofilaments, neurotubules, axonal mitochondria

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