https://doi.org/10.31288/oftalmolzh201426671

Morphological peculiarities of the retina, nerve fiber layer and choroidea in patients after posttraumatic endophthalmitis

T. A. Krasnovid, N. P. Grubnyk, Ivanitskaya E. V, A. N. Kurilyuk

State Institution The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine, Odessa, (Ukraine)

Introduction: Examination of morphological and morphometric features of the retina, retinal nerve fiber layer, choroidea in patients with posttraumatic endophthalmitis after pars plana lens vitrectomy using spectral-domain optical coherence tomography is very important for understanding its development and search for new complex methods of treatment.

Purpose. To study morphological and morphometric features of the retina, retinal nerve fiber layer, choroidea in patients with posttraumatic endophthalmitis after pars plana lens vitrectomy using spectral-domain optical coherence tomography (OCT) by Spectralis (Heidelberg Engineering).

Material and methods. We observed 11 patients (11 eyes) with posttraumatic endophthalmitis. Pars plana lens vitrectomy was performed in all cases in terms of 3—28 days after injury. 1 month after surgery the retina and retinal nerve fiber layer were examined in 5patients, choroidea — in 4patients using OCT. Results. Our data show increase of the macular retinal thickness especially in the central region. Thickness of the retinal nerve fiber layer also increased in the trauma-tized eyes. Choroidal thickness decreased in the macular andparapapillar regions.

Conclusion. It was first of using spectral-domain optical coherence tomography by Spectralis (Heidelberg Engineering) in patients with posttraumatic endophthalmitis after pars plana lens vitrectomy. In our cases we observed increase of the retinal thickness in the macular region, increase of thickness of the retinal nerve fiber layer, decrease of choroidea in the macular and parapapillar regions.

Key words: posttraumatic endo-phthalmitis, retinal nerve fiber layer, choroidea

References

1.Aliyev FD, Sharipova DN, Yarakhmedova IB et al. Clinical analysis of complex surgical treatment of endophthalmitis. Modern technologies of vitreoretinal pathology. Collec¬tion of papers of scientific practical conference. Moscow; 2012. 18- 22. Russian.

2.Gundorova RA, Neroiev VV, Kashnikov VV. Traumas of the eye. Moscow; 2009. 383- 93.

3.Zborovskaya AV. Experimental and clinical rationale and effectiveness of antimicrobial photodynamic therapy in patients with severe keratitis and endophthalmitis: author's thesis for Doctor of Med. Science. Odessa. 2012. 30 p.

4.Logai IM, Rodin SS. Exogenous bacterial endophthalmitis. Odessa; 1996. 152 p.

5.Yuzhakov AM, Gundorova RA, Neroiev VV, Stepanov AV. Intraocular wound infection. Medical information agency. Moscow; 2007. 239 p.

6.Aggarwal P. Posttraumatic endophthalmitis with retained intraocular foreign body a case report with review of literature:Aggarwal et al. Nepal J Ophthalmol. 2012. Vol.7:187- 90.

7.Ahmed Y. Endophthalmitis following open-globe injuries. Y Ahmed et al. Eye (Lond). 2012 ;26 (2):212-7.
Crossref

8.Bhagat N. Post-traumatic Infectious Endophthalmitis. N. Bhagat, S. Nagori, M. Zarbin. Survey of ophthalmology. 2011. Volume 56 (3). P.214-251.
Crossref

9.Brington G. S., Topping TM, Hynduik RA, et al. Posttraumatic endophthalmitis. Arch Ophthalmol 1984;102:547- 550.
Crossref

10.Caio V. Regatieri Choroidal imaging using spectral-domain optical coherence tomography. Caio V. Regatieri, L Branchini, BA, J G. Fujimoto, J S. Duker. Retina. 2012. — Vol. 32(5):865- 876.
Crossref

11.Fujiwara T Enhanced depth imaging optical coherence tomography of the choroid in highly myopic eyes. T Fujiwara, Y Imamura, R Margolis et al.. Am J Ophthalmol. 2009; 148:445-450.
Crossref

12.Gardner TW Diabetic retinopathy: more than meets the eye. TW Gardner, DA Antonetti, AJ Barber et al. Surv Ophthalmol. 2002 ;47:253-262.
Crossref

13.Guex-Crosier Y. The pathogenesis and clinical presentation of macular edema in inflammatory diseases. Y Guex-Crosier. Doc Ophthalmol. 1999 ;97:297- 309.

14.Hooshang Faghihi Posttraumatic endophthalmitis report no. 2. Hooshang Faghihi et al. Retina. 2012 ;32(1):146-151

15.Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29:1469- 73.

16.Mansouri M et al. Epidemiology of open globe injuries in Iran: analysis of 2,340 cases in 5 years (report no. 1). Retina. 2009;29:1141-9.

17.Margolis R, Spaide RF. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009;147:811-5.

18.Marion R Munk. Morphologic and functional evaluations during development, resolution, and relapse of uveitis-as-sociated cystoids macular edema. Retina. 2013;33:1673- 83.

19.Mieler WF et al. Retained intraocular foreign bodies and endophthalmitis. Ophthalmology. 1990;97(11):1532-8.

20.Mrejen S, Spaide RF. Imaging the Choroid in Uveitis. International ophthalmology clinics. 2012;52(4):67-81.

21.Novosad BD, Callegan MC. Severe bacterial endophthalmitis: towards improving clinical outcomes. Expert Rev Ophthalmol. 2010;Oct 5(5):689- 98.

22.Spaide RF. Age-related choroidal atrophy. Am J Ophthalmol. 2009;147:801- 10.

23.Thompson JT et al. Infectious endophthalmitis after pen-etrating ocular injuries with retained intraocular foreign bodies. Ophthalmology. 1993;Oct 100(10):1468- 74.

24.Tranos PG Macular edema. Surv Ophthalmol. 2004; 49: 470-90.

25.van Kooij B, Rothova A, Rijkers GT, de Groot-Mijnes JD. Distinct cytokine and chemokine profiles in the aqueous of patients with uveitis and cystoid macular edema. Am J Ophthalmol. 2006;142:192- 4.
Crossref