J.ophthalmol.(Ukraine).2018;6:19-22.

http://doi.org/10.31288/oftalmolzh201861922

Received: 11 September 2018; Published on-line: 30 December 2018


Choroidal thickness in patients with progressive and stabilized POAG

M.V. Panchenko, Prof, Dr Sc (Med), I.G. Duras, Cand Sc (Med), O.M. Honchar, Cand Sc (Med), D.O. Prykhodko, MD, A.S. Pereiaslova, MD, L.G. Avilova, MD

Kharkiv National Medical University;  

Kharkiv (Ukraine) 

E-mail: panchenko0802@gmail.com

TO CITE THIS ARTICLE: Panchenko MV ,   Duras IG,  Honchar OM,  Prykhodko DO, Pereiaslova AS, Avilova LG.Choroidal thickness in patients with progressive and stabilized POAG. J.ophthalmol.(Ukraine).2018;6:19-22. http://doi.org/10.31288/oftalmolzh201861922   

 

Purpose: To investigate choroidal thickness in patients with progressive and stabilized primary open-angle glaucoma (POAG).

Materials and Methods: Forty-nine patients (87 eyes; age, 52 to 77 years) with stage 1, 2 or 3 POAG were involved in the study. Choroidal thickness was measured with optical coherence tomography.

Results: The foveal choroidal thickness and peripapillary choroidal thickness were thinner in progressive POAG versus stabilized glaucoma (184.2±20.6 µm vs 261.1±19.4 µm, p<0.05; and 184.2±20.6 µm vs 261.1±19.4 µm, p>0.05, respectively). Foveal choroidal thickness was directly correlated with ganglion cell complex thickness (r=0.5725, p < 0.05), and negatively correlated with progressive POAG (r=-0.4246, p < 0.05).

Conclusion: In patients with POAG, foveal choroidal thickness is directly correlated with ganglion cell complex thickness and disease progression. The foveal choroidal thickness and peripapillary choroidal thickness were 31% and 23%, respectively, thinner in progressive POAG versus stabilized POAG.

Keywords: progressive and stabilized POAG, choroidal thickness

References

1.Yin ZQ, Vaegan, Millar TJ, Beaumont P, Sarks S. Widespread choroidal insufficiency in primary open-angle glaucoma. J Glaucoma. 1997 Feb;6(1):23-32.
Crossref   Pubmed

2.Spraul CW, Lang GE, Lang GK, Grossniklaus HE. Morphometric changes of the choriocapillaris and the choroidal vasculature in eyes with advanced glaucomatous changes. Vision Res. 2002 Mar;42(7):923-32.
Crossref   Pubmed

3.Hirooka K, Fujiwara A, Shiragami C, et al. Relationship between progression of visual field damage and choroidal thickness in eyes with normal-tension glaucoma. Clin Exp Ophthalmol. 2012 Aug;40(6):576-82.
Crossref   Pubmed

4.Usui S, Ikuno Y, Miki A, et al. Evaluation of the choroidal thickness using high-penetration optical coherence tomography with long wavelength in highly myopic normal-tension glaucoma. Am J Ophthalmol. 2012 Jan;153(1):10-6.e1. doi: 10.1016/j.ajo.2011.05.037.
Crossref   Pubmed

5.Kurysheva NI, Ardzhevnishvili TD, Kiseleva TN, Fomin AV. [The choroid in glaucoma: the results of a study by optical coherence tomography].  Natsional’nyi zhurnal glaukoma. 2013;4:72-83. Russian.

6.Kurysheva NI, Boyarinceva MA, Fomin AV. [Choroidal thickness in primary angle-closure glaucoma: the results of Measurement by Means of Optical Coherence Tomography].  Ophthalmology in Russia. 2013; 10(4):26-31. Russian. https://doi.org/10.18008/1816-5095-2013-4-26-31

7.Cennamo G, Finelli M, Iaccarino G, de Crecchio G. Choroidal thickness in open-angle glaucoma measured by spectral-domain scanning laser ophthalmoscopy/optical coherence tomography. Ophthalmologica. 2012;228(1):47-52. doi: 10.1159/000336903.
Crossref   Pubmed

8.Rhew JY, Kim YT, Choi KR.. Measurement of subfoveal choroidal thickness in normal-tension glaucoma in Korean patients. J Glaucoma. 2014 Jan;23(1):46-9. doi: 10.1097/IJG.0b013e31825af772.

9.Ehrlich JR, Peterson J, Parlitsis G, et al. Peripapillary choroidal thickness in glaucoma measured with optical coherence tomography. Exp Eye Res. 2011;92:189–94.

10.Maul EA, Friedman DS, Chang DS, et al. Choroidal thickness measured by spectral domain optical coherence tomography: factors affecting thickness in glaucoma patients. Ophthalmology. 2011 Aug;118(8):1571-9. doi: 10.1016/j.ophtha.2011.01.016.

11.Mwanza J-C, Sayyad FE, Budenz DL. Choroidal thickness in unilateral advanced glaucoma. Invest. Ophthalmol Vis Sci. 2012 Sep 28;53(10):6695-701.

12.Mwanza JC, Hochberg JT, Banitt MR, et al. Lack of association between glaucoma and macular choroidal thickness measured with enhanced depth-imaging optical coherence tomography. 2011 May 18;52(6):3430-5. doi: 10.1167/iovs.10-6600.