J.ophthalmol.(Ukraine).2021;5:14-20.

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http://doi.org/10.31288/oftalmolzh202151420

Received: 24 May 2021; Published on-line: 23 October 2021


Evaluation of corneal distortion characteristics in different eyes using Scheimpflug camera device

Sbordone S., MD, Ragucci A., MD, Iaccarino G., MD, Scognamiglio G., MD, Serra L., MD, Gironi Carnevale U.A., PhD, Lanza M., MD, PhD

Dipartimento Multidisciplinare di Specialità Mediche, Chirurgiche e Odontoiatriche, Università degli studi della Campania “L. Vanvitelli”

Napoli (Italy)

E-mail: mic.lanza@gmail.com

TO CITE THIS ARTICLE: Sbordone S, Ragucci A, Iaccarino G, Scognamiglio G, Serra L, Gironi Carnevale UA, Lanza M. Evaluation of corneal distortion characteristics in different eyes using Scheimpflug camera device. J.ophthalmol.(Ukraine).2021;5:14-20.http://doi.org/10.31288/oftalmolzh202151420


Objective. To study the correlations between corneal distortion and morphological features in different kinds of eyes such as healthy ones (HE), ones previously undergone myopic PRK (PRKE), ones affected by keratoconus (KCE) and keratoconus eyes previously undergone corneal collagen crosslinking (CCCE). 

Materials and Methods. In this retrospective comparative study, a total of 106 HE of 106 patients, 58 PRKE of 58 patients, 33 KCE of 33 patients, 28 CCCE of 28 patients were included. A complete examination of all eyes was followed by tomographic (Pentacam, Oculus, Wetzlar, Germany) and biomechanical (Corvis ST, Oculus, Wetzlar, Germany) evaluation. Differences among Corvis ST (CST) parameters in the different groups have been analyzed. Linear regressions between central corneal thickness (CCT), intraocular pressure (IOP) and anterior corneal curvature measured with Simulated Keratometry (SK), versus corneal deformation parameters measured with Corvis ST in the different groups, have been run using SPSS software version 18.0. 

Results, HE showed a significant correlation between main curvature power of the cornea within the central 3 mm expressed in Diopters (KM) and 6 CST parameters; between CCT and 4 CST parameters and between IOP and 5 CST parameters. PRKE showed a significant correlation between KM and 3 CST parameters; between IOP and 4 CST parameters and none between CCT and CST parameters. KCE showed a significant correlation between SK and 3 CST parameters; between IOP and 3 CST parameters and none between CCT and CST parameters. CCCE showed a significant correlation between KM and 5 CST parameters; between CCT and 1 CST parameters and between IOP and 5 CST parameters. 

Discussion. Data of this study suggest that both corneal curvature and IOP could have a greater influence on the corneal deformation, compared to central corneal thickness (CCT). These results should be taken into account by further studies aiming to assess biomechanical corneal characteristics.

Кey words: сorneal deformation; corneal crosslinking; Corvis ST, keratoconus, refractive surgery

 

References

1.Luce DA. Determining in vivo biomechanical properties of the cornea with an ocular response analyzer. Journal of  Cataract and Refractive Surgery. 2005;(31):156-162.

Crossref  PubMed

2.Martinez-de-la-Casa JM, Garcia-Feijoo J, Fernandez-Vidal A, Mendez-Hernandez C, Garcia-Sanchez J. Ocular Response Analyzer versus Goldmann Applanation Tonometry for Intraocular Pressure Measurements. Investigative Ophthalmology & Visual Science. 2006;(47):4410-4414.

Crossref  PubMed

3.Terai N, Raiskup F, Haustein M, Pillunat LE, Spoerl E.Identification of biomechanical properties of the cornea: the ocular response analyzer. Current Eye Research. 2012;(37):553-562.

Crossref  PubMed

4.Hurmeric V, Sahin A, Ozge G, Bayer A. The relationship between corneal biomechanical properties and confocal microscopy findings in normal and keratoconic eyes. Cornea. 2010;(29):641-649.

Crossref  PubMed

5.McMonnies CW. Assessing corneal hysteresis using the Ocular Response Analyzer. Optometry and Vision Science. 2012;(89):E343-349.

Crossref  PubMed

6.Kotecha A, Elsheikh A, Roberts CR, Zhu H, Garway-Heath DF. Corneal Thickness and Age Related Biomechanical Properties of the Cornea Measured with the Ocular Response Analyzer. Investigative Ophthalmology & Visual Science. 2006;(47):5337-5347.

Crossref  PubMed

7.Narayanaswamy A, Chung RS, Wu RY, Park J, Wong WL, Saw SM et al. Determinants of corneal biomechanical properties in an adult Chinese population. Ophthalmology. 2011;(118):1253-1259.

Crossref  

8.Ma, J.; Wang, Y.; Wei, P.; Jhanji, V. Biomechanics and structure of the cornea: implications and association with corneal disorders. Surv Ophthalmol. 2018, 63, 851-861

Crossref  PubMed

9.Lanza, M.; Iaccarino, S.; Bifani, M. In vivo human corneal deformation analysis with a Scheimpflug camera, a critical review. J Biophotonics. 2016, 9, 464-77

Crossref  PubMed

10.Ortiz D, Piñero D, Shabayek MH, Arnalich-Montiel F, Alió JL.Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes. Journal of  Cataract and Refractive Surgery. 2007;(33):1371-1375.

Crossref  PubMed

11.Liu J, Roberts CJ. Influence of corneal biomechanical properties on intraocular pressure measurement: quantitative analysis. Journal of Cataract and Refractive Surgery. 2005;(31):146-155.

Crossref  PubMed

12.Kara N, Altinkaynak H, Baz O, Goker Y. Biomechanical Evaluation of Cornea in Topographically Normal Relatives of Patients With Keratoconus. Cornea. 2013;(32):262-266.

Crossref  PubMed 

13.Kotecha A. What biomechanical properties of the cornea are relevant for the clinician?. Survey Ophthalmology. 2007;(52):109-114.

Crossref  PubMed

14.Lanza M, Cennamo M, Iaccarino S, Romano V. et al., Bifani M, Irregolare C, Lanza A. Evaluation of corneal deformation analyzed with a Scheimpflug based device. Cont Lens Anterior Eye. 2015 Apr;38(2):89-93.

Crossref  PubMed

15.Rosa N, Lanza M, De Bernardo M, Signoriello G, Chiodini P. Relationship Between Corneal Hysteresis and Corneal Resistance Factor with Other Ocular Parameters. Semin Ophthalmol. 2015;30(5-6):335-339

Crossref  PubMed

16.Huseynova T, Waring GO 4th, Roberts C, Krueger RR, Tomita M. Corneal biomechanics as a function of intraocular pressure and pachymetry by dynamic infrared signal and scheimpflug imaging analysis in normal eyes. American Journal of Ophthalmology.2014;157:885-893

Crossref  PubMed

17.Ma, J.; Wang, Y.; Wei, P.; Jhanji, V. Biomechanics and structure of the cornea: implications and association with corneal disorders. Surv Ophthalmol. 2018, 63, 851-861

Crossref  PubMed

18.Reznicek L, Muth D, Kampik A, Neubauer AS, Hirneiss C. Evaluation of a novel Scheimpflug-based non-contact tonometer in healthy subjects and patients with ocular hypertension and glaucoma. British Journal of Ophthalmology. 2013;97:1410-1414.

Crossref  PubMed 

19.Kuryan, J.; Cheema, A.; Chuck, R.S. Laser-assisted subepithelial keratectomy (LASEK) versus laser-assisted in-situ keratomileusis (LASIK) for correcting myopia. Cochrane Database Syst Rev. 2017, 2, CD011080.

Crossref  PubMed

20.Herber, R.; Vinciguerra, R.; Lopes, B.; Raiskup, F. et al. Repeatability and reproducibility of corneal deformation response parameters of dynamic ultra-high-speed Scheimpflug imaging in keratoconus. J Cataract Refract Surg. 2020, 46, 86-94.

21.Yu, M.; Chen, M.; Dai, J. Comparison of the posterior corneal elevation and biomechanics after SMILE and LASEK for myopia: a short- and long-term observation. Graefes Arch Clin Exp Ophthalmol. 2019, 257, 601-606.

Crossref  PubMed

22.Hashemi, H.; Asgari, S.; Mortazavi, M.; Ghaffari, R. Evaluation of Corneal Biomechanics After Excimer Laser Corneal Refractive Surgery in High Myopic Patients Using Dynamic Scheimpflug Technology. Eye Contact Lens. 2017, 43, 371-377.

Crossref  PubMed

23.Lanza M, De Rosa L, Sbordone S, Boccia R, Gironi Carnevale UA, Simonelli F. Analysis of Corneal Distortion after Myopic PRK. J Clin Med. 2020 Dec 28;10(1):82. doi: 10.3390/jcm10010082.

Crossref  PubMed

24.Guo, H.; Hosseini-Moghaddam, S.M.; Hodge, W. Corneal biomechanical properties after SMILE versus FLEX, LASIK, LASEK, or PRK: a systematic review and meta-analysis. BMC Ophthalmol. 2019, 19, 167.

Crossref  PubMed 

25.Abd Elaziz, M.S.; Elsobky, H.M.; Zaky, A.G.; Hassan, E.A.M.; KhalafAllah, M.T. Corneal biomechanics and intraocular pressure assessment after penetrating keratoplasty for non keratoconic patients, long term results. BMC Ophthalmol. 2019, 19, 172.

Crossref  PubMed

 

Conflict of interest statement: None.

Funding sources: None

 

Received 24.05.21