Oftalmol Zh.2011;4:71-76.
http://doi.org/10.31288/oftalmolzh201147176
INFLUENCE OF GLYCINE ON DEVELOPMENT OF THE LENS OPACITY AND STATE OF THE ENZYMATIC ANTIOXIDANT SYSTEM IN MODELING OF EXPERIMENTAL CATARACT UNDER THE CONDITIONS OF STREPTOZOTOCIN DIABETES
Leus N. F., Ben Abdallah Anis, Zhuravok Yu.A.
Odessa, Ukraine
In modeling of light cataract and streptozotocin diabetes in rabbits there was noted the expressed development of pathologic changes and disturbance of the activity of the antioxidant system (superoxidedismutase, glutathion-peroxidase, catalase) in the lens. The application of glycine exerted the stabilizing effect on the lens components and prevented the disturbance of the activity of antioxidant enzymes.
References
1.Бабижаев М. А. Накопление продуктов перекисного окисления липидов в хрусталике при катаракте / Бабижаев М. А., Шведова А. А., Архипенко Ю. В. // Бюл. экспер. биол. — 1985. — № 9. — С. 299- 301.
2.Веселовская 3. Ф. Катаракта / Веселовская 3. Ф., Боброва Н. Ф., Вит В. В. // Киев: Книга плюс. — 2002. — 208 с.
3.Королюк М. А., Л. И. Иванова, И. Г. Майорова, B.Е. Токарев. Метод определения активности каталазы // Лаб. Дело. — 1988. — № 1. — 16-18 с.
4.Леус Н. Ф. О пусковых механизмах катарактогенеза / Леус Н. Ф. // Офтальмол. журн. — 1985. — № 7. — C.430-434.
5.Наследов А. SPSS компьютерный анализ данных в психологии и социальных науках. // Спб.: Питер, 2005. — 416 с.
6.Alvarado-Vasquez N. Effect of glycine in streptozotocin-induced diabetic rats / Alvarado-Vasquez N., Zamudio P., Ceron E. // Comp. Biochem. Physiol. Part C. — 2003. — Vol. 134. — P. 521- 527.
Crossref
7.Alvarado-Vasqueza N. Oral glycine administration attenuates diabetic complications in streptozotocin-induced diabetic rats / Alvarado-Vasqueza N., Lascurainb R., Cerons E. // Life Sci. — 2006. — Vol. 79. — № 3. — P. 225-232.
Crossref
8.Aragon M. C. Stoichiometry of sodium- and chloride-coupled glycine transport in synaptic plasma membrane vesicles derived from ratbrain / Aragon M. C., Gimenez C., Mayor F // FEBS Lett. — 1987. — Vol. 212. — P. 87- 90.
Crossref
9.Aubrey K. R. Molecular basis for proton regulation of glycine transport by glycine transporter subtype 1b / Aubrey K. R., Mitrovic A. D., Vandenberg R. J. // Mol. Pharmacol. — 2000. — Vol. 58. — P. 129- 135.
Crossref
10.Blackburn S. Determination of glycine / Blackburn S. // Amino Acid determination methods and techniques, Marcel Dekker. — 1968. — P. 196- 197.
11.Bunce G. Nutritional factors in cataract / Bunce G., Kinoshita J. // Ann. Rev. Nutr. — 1990. — Vol. 10. — P. 233-254.
Crossref
12.Cumming R. G. Diet and cataract / Cumming R. G., Mitchell P., Smith W. // Ophthalmology. — 2000. — Vol. 107. — P. 450-456.
Crossref
13.Donma O. Blood and lens lipid peroxidation and antioxidant status in normal individuals, senile and diabetic cataractous patients / Donma O., Yorulmaz E., Pekel H. // Curr. Eye Res. — 2002. — Vol. 25. — P. 9-16.
14.Hodge W. G. Risk factors for age related cataracts / W. G. Hodge, J. P. Whitcher // Epidemiol. Rev. — 1995. — № 17. — P. 336- 346.
15.Knudtson M. D. Age-related eye disease, quality of life, and functional activity / Knudtson M. D., Klein B. E., Klein R. // Arch Ophthalmol. — 2005. — Vol. 123 (6). — P. 807-814.
16.Laurent M. Transport of amino acids into the lens in the course of experimental diabetic cataract / Laurent M., Kern P., Regnault F. // Ophthalm. Res. — 1972. — Vol. 4. — P. 114-121.
17.Leus N. F. Lens coenzymes and cataract formation / Leus N. F. // lens and Eye Toxicity Res. — 1991. —Vol. 283. — № 8. — P. 1113-1119.
18.Lim J. Mapping of glutathione and its precursor amino acids reveals a role for GLYT2 in Glycine uptake in the lens core / Lim J., Li L., Jacobs M. D., Kistler J. // Invest. OPhthalmol. Vis. Sci. — 2007. — Vol. 48. — P. 5142-5151.
19.Lim J. Molecular identification and characterization of the glycine transporter (GLYT1) and the glutamine/ glutamate transporter (ASCT2) in the rat lens / Lim J., Lorentzen K. A., Kistler J. // Exp. Eye Res. — 2006. — Vol. 83. — № 2. — P. 447-455.
20.Lopez-Corcuera B. Differential properties of two stably expressed brain-specific glycine transporters / Lopez-Corcuera B., Martinez-Maza R., Nunez E. // J. Neurochem. — 1998. — Vol. 71. — P. 2211- 2219.
21.Maurya O. P. S. Role of antioxidant enzymes superoxide dismutase and catalase in the development of cataract: study of serum levels in patients with senile and diabetic cataracts / Maurya O. P. S., Mohanty L. // AIOC PROCEEDING. — 2006. — Vol. 24. — P. 142-143.
22.Meyer C. H. Nutritional supplementation to prevent cataract formation / C. H. Meyer, W. Secundo // Dev Ophthalmol. — 2005. — Vol. 38. — P. 103-119.
23.Mitchell P. Nutritional factors in the development of age-related eye disease / Mitchell P., Smith W., Cumming R. G. // Asia Pac J. Clin. Nutr. — 2003. — Vol. 12. — P. 32-35.
24.Oimomi M. Glycation of cataractous lens in non-diabetic senile subject and in diabetic patients / Oimomi M., Maeda Y., Hata F. // Exp. Eye Res. — 1988. — Vol. 46. — P. 415-420.
25.Ramakrishnan S. Decrease in glycation of lens proteins by lysine and glycine by scavenging of glucose and possible mitigation of cataractogenesis / Ramakrishnan S., Sulochana K. N. // Exp. Eye Res. — 1993. — Vol. 57. — P. 623-628.
26.Ramakrishnan S. Free alanine, aspartic acid, or glutamic acid reduce the glycation of human lens proteins / Ramakrishnan S., Sulochana K. N., Puitham R. // Glycoconjugate J. — 1996. — Vol. 13. — № 4. — P. 519-523.
27.Ramakrishnan S. Free lysine, glycine, alanine, glutamic acid and aspartic acid reduce the glycation of human lens proteins by galactose / Ramakrishnan S., Sulochana K. N., Puitham R. // Ind. J. Biochem. Biophys. - 1997. - Vol. 34. - № 6. - P. 518- 523.
28.Robman L. D. External factors in the development of cataract / Robman L. D., Taylor H. // Eye. - 2005. - Vol. 19 (10). - P. 1074- 1082.
29.Supplisson S. Why glycine transporters have different stoichiometries / Supplisson S., Roux M. J. // FEBS Lett. - 2002. - Vol. 259. - P. 93-101.
30.Tunnicliff G. Membrane glycine transport proteins / Tunnicliff G. // J. Biomed. Sci. - 2003. - Vol. 10. - P. 30- 36.