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http://doi.org/10.31288/oftalmolzh2012692100

INFLUENCE OF THE EYE DROP PRESERVATIVES ON THE RESTORATIVE POTENTIAL OF GLUTATHIONE IN THE TISSUES OF THE ANTERIOR SECTION OF THE EYE

Gaidamaka T. B., Senishin V. I.

Odessa, Ukraine

There was determined the level of oxidated and restored glutathione in the cornea, conjunctiva and lacrimal fluid after instillations of 0.02 % solution BAC prepared on the isotonic phosphate buffer (pH 7.3-7.4) in the experiment on the animals (17 rabbits).

It was found that the preservative under study significantly decreased the level of the restored glutathione and increased the level of oxidated glutathione, which was evidence of disorder of the disintoxication system of glutathione resulting in reduction of the protective possibilities of the anterior section of the eye resistance of the eye to viral infection.

 

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