https://doi.org/10.31288/oftalmolzh201325660

Intravitreal ranibizumab injection in the treatment of cystoid diabetic macular edema

N. N. Umanets, Z. A. Rozanova, Maher Alzein

SI «Filatov Institute of Eye Diseases and Tissue Therapy of National Academy of Medical Sciences of Ukraine»

Key words: diabetic macular edema, ranibizumab, intravitreal injection.

The aim of the study was to investigate the efficacy of intravitreal injection of 0,5 mg ranibizumab in the treatment of cystoid diabetic macular edema as a monotherapy. In the study was included 41 eyes (type I of diabetes mellitus — 31 patient, type II of diabetes mellitus — 19 patients, blood glucose less than 13,0pMol/l) non-proliferative diabetic retinopathy (DR) — 78,0 %, preproliferative DR — 14,6 %, proliferative DR — 7,4 %. Macular thickness (MT) and foveal avascular zone (FAZ) in fluorescent angiography images and best corrected visual acuity (BCVA) were measured. During the year 1 bevacizumab injection to 7,3 %, 2 injections to 24,4 % and 3 injections to 68,3 % of patients were done. After the one year of the start of treatment MT significantly reduced from 506±20 pm to 376±21,9 pm, FAZ reduced from 1,1±0,24 mm2 do 0,9±0,24 mm2 and BCVA increased or stabilized in 63,4 % patients.