Oftalmol Zh.2014;2:44-48

https://doi.org/10.31288/oftalmolzh201424448

Topographic peculiarities of central serous chorioretinopathy depending on the form of the diseases and infection with the causative agent helicobacter pylory

P. A. Bezdetko, I. M. Lagorzhevska, O. V. Zavoloka

Kharkov National Medical university, Kharkov (Ukraine)

Key words: central serous chorioretinopathy, acute form, chronic form, retinal tomography, Helicobacter Pylori.

Introduction. The frequency of Helicobacter Pylori (HP) infection among patients with central serous chorioretinopathy (CSC) exceeds general national one.

Purpose. To determine tomographic peculiarities of the central serous chorioretinopathy depending on the form of the disease and Helicobacter Pylori infection.

Materials and methods. 93 patients with acute form, 15 — with primary chronic and 36 (44 eyes) with secondary chronic form of central serous chorioretinopathy were examined with the help of spectral OCT on the tomograph «SOCT Copernicus».

Results. HP-positive patients with CSC are characterized by: frequency of combined neuro- and pigment retinal epithelium detachment (15.9 % eyes) was 2.1 times higher (p<0.0l), neuroepithelium detachment only (84.1 % eyes) -1.1 times lower (p[<0.05) than indices of HP-negative patients; height of the sack with sub-retinal fluid (219+82 nm) was 1.3 times lower, its width (3690+448 nm) — 1.2 times higher than indices of HP-negative patients (p[<0.05); central (175+17 nm) and general central foveal retinal thickness (395+40 nm) was 1.3 times decreased than indices of HP-negative patients (p[<0.05).

Conclusions. Retinal tomographic peculiarities in patients with central serous chorioretinopathy depend on the form of the disease and Helicobacter Pylori infection. 

References

1. Koskas G, Zurdan A. Complex diagnosis of eye fundus pathology (fluorescent angiography, indocian angiography, optic coherent tomography). Neroiev VV, Ryabina MV, editors. M.: Prakticheskaya meditsina; 2007. 175 p.

2. Chikovani KR. Diagnostic criteria and differentiated approach to the treatment of various forms of central serous chorioretinopathy: thesis of Candidate of Medical Sci¬ence: 14.00.08. Moscow. 2011. 137 p.

3.Franceschi F., Niccoli G., Ferrante G et al. CagA antigen of Helicobacter pylori and coronary instability: insight from a clinico-pathological study and a meta-analysis of 4241 cases. Atherosclerosis. 2009;202:535- 42.
Crossref

4.Cotticelli L, Borrelli M, D'Alessio AC et al. Central serous chorioretinopathy and Helicobacter pylori. European journal of ophthalmology. 2006;16(2):274- 8.
Crossref

5.Kitaya N, Nagaoka T, Hikichi T et al. Features of abnormal choroidal circulation in central serous chorioretinopathy. Br J Ophthalmol. 2003;87:709- 12.
Crossref

6.Giusti C. Central serous chorioretinopathy: a new extra-gastric manifestation of Helicobacter pylori?: Analysis of a clinical case. Clin Ter. 2001;152:393- 7.

7.Giusti C, Mauget-Fansse M. Helicobacter pylori and idiopathic central serous chorioretinopathy. Swiss Med Wkly. 2004;134:395-8.

8.Franceschi F, Navarese EP, Mollo R et al. Helicobacter pylori and atherosclerosis. A review of the literature. Recenti Prog Med. 2009;100:91-6.

9.Whittle BJR, Morschl E, Pozsafr J et al. Helicobacter pylori lipopolysaccharide provokes iNOS-mediated acute systemic microvascular inflammatory responses in rat cardiac, hepatic, renal and pulmonary tissues. J Physiol Paris. 2001;95:257- 9.
Crossref

10.Manolakis A, Kapsoritakis AN, Potamianos SP. A review of the postulated mechanisms concerning the association of Helicobacter pylori with ischemic heart disease. Helicobacter. 2007;12:287- 97.
Crossref

11.Misiuk-Hojlo M, Michalowska M, Turno-Krecicka A. Helicobacter pyloria risk factor for the development of the central serous chorioretinopathy. Klin Oczna. 2009;111:30-2.

12.Piccolino FC, de la Longrais RR, Ravera G et al. The foveal photoreceptor layer and visual acuity loss in central serous chorioretinopathy. Am J Ophthalmol. 2005;139:87-99.
Crossref

13.Kitzmann AS, Pulido JS, Diehl NN et al. The incidence of central serous chorioretinopathy in Olmsted County, Min-nesota, 1980- 2002. Ophthalmology. 2008;115:169- 73.
Crossref