J.ophthalmol.(Ukraine).2018;1:3-6.

http://doi.org/10.31288/oftalmolzh2018136


Assessing the efficacy of surgical treatment for age-related cataract through risk factor analysis

I.M. Bezkorovaina, Dr Sc (Med), Prof., I.S. Steblovska, Post-Grad Student

Ukrainian Medical Stomatological Academy; Poltava (Ukraine)

E-mail: irunasteblovska@gmail.com             

TO CITE THIS ARTICLE: Bezkorovaina IM, Steblovska IS. Assessing the efficacy of surgical treatment for age-related cataract through risk factor analysis. J.ophthalmol.(Ukraine).2018;1:3-6. http://doi.org/10.31288/oftalmolzh2018136

    

Background: Although conventional phaco and femtosecond laser-assisted cataract surgery are widely used treatment options, patients undergoing these approaches often experience peri- and post-operative complications that worsen functional outcomes. Cystic macular edema is one of these complications and occurs in 1-28% of patients.

Purpose: To assess the efficacy of surgical treatment for age-related cataract through risk factor analysis using logistic regression models.

Materials and Methods: Eighty-three eyes of 83 patients with age-related cataract (lens nuclei of grades 1 to 3, Buratto classification scheme) participated in the study. Aqueous humor samples were collected during phacoemulsification procedures and investigated for the presence of prostanoids, thromboxane B2 and prostacyclin 6-keto-PGF1α. A negative outcome of surgical treatment for cataract was defined as development of macular edema; any other outcome was considered positive.

Results: 6-keto-PGF1α/ thromboxane B2 ratio can be used as a marker of the risk for developing macular edema 1 year after phacoemulsification for age-related cataract.

Key-words: logistic regression models, age-related cataract, macular edema    

 

References

  1. Astakhov SYu, Gobedzhishvili MV. [Postoperative macular edema, Irvine–Gass syndrome]. Klinicheskaia oftalmologiia. 2010;11(1):5–8. Russian
  2. Batmanov YE, Evgrafov VY. [Cataract]. Moscow: Meditsina; 2005. Russian
  3. Bezkorovayna IM, Voskresenska LK, Riadnova VV, Shatkun AA. [Clinical peculiarities of pathological changes in the retina depending o the type of diabetes mellitus]. Vrachebnoie delo. 2016;7-8:104-5
  4. Gobedzhishvili MV, Astakhov SYu, Kugleev AA. [Macular edema in pseudophacia]. Oftalmologicheskie vedomosti. 2011; 4(4):57–9. Russian
  5. American Academy of Ophthalmology. Cataract in the Adult Eye. Cataract and Anterior Segment Preferred Practice Pattern (PPP) Panel. Accessed June 2, 2015. www.aao.org/preferred-practice-pattern/cataract-in-adult-eye-ppp--octobe...
  6. Lebraud P, Adenis JP, Franco JL, et al. Cystoid macular edema of pseudophakic patients (retrospective study with 300 pseudophakic patients). Bull Soc Ophthalmol Fr. 1987 Dec;87(12):1437-9