http://doi.org/10.31288/oftalmolzh201051216

INTERRELATION OF THE CLINICAL AND FUNCTIONAL MANIFESTATIONS AND PATHOMORPHOLOGICAL CHANGES IN THE CORNEA IN THE PATIENTS WITH HERPETIC KERATITIS

T. B. Gaydamaka, G. I. Drozhzhina, N. I. Khramenko, N. E. Dumbrova

Odessa, Ukraine

Purpose. To study the association between the peculiarities of the clinical and functional manifestations and pathomorphological changes in the cornea in the patients with herpetic keratitis and work out the prognostic criteria of the inflammatory process activity. Studies are carried out on the corneal disks obtained during the operation of keratoplasty in 40 patients with relapsing stromal HK. There was established nonconformity between the peculiarities of the clinical picture and pathomorphological changes in the cornea in herpetic keratitis: in the stage of clinical remission the inflammatory process is diagnosed pathomorphologically in 17.4 % of patients, and in the aggravation degenerate changes only are diagnosed in 17.6 % of patients. In herpetic keratitis the level of hyperemia of the sick eye is reliably reduced in the group with the degenerate morphological changes (l. 78±0.64SD (%o) both in comparison with the control (RQ=3.2±l.08SD (%) and in comparison with other groups (with the inflammatory and inflammatory-degenerate changes (RQ=3.65S±0.94SD (%) and 3.09±1.21SD (%) respectively), and are the criterion allowing to prognose the nature of the pathologic process in the eye.

References

1.Алексеев В. Н., Литвин И. Б. Толщина роговицы как фактор риска развития первичной открытоугольной глаукомы // РМЖ Клиническая офтальмология. — 2009. — Т. 10, № 3. — С. 86- 88.

2.Катаргина Л. А., Киселева О. А., Арутюнян Л. Л. и со-авт. Значение центральной толщины роговицы в прогрессировании первичной открытоугольной глаукомы // Новости глаукомы. — 2010. — № 1. — C. 3-5.

3.Christensen A., NarvGez J., Zimmerman G. Comparison of central corneal thickness measurements by ultrasound pachymetry,   Konan  noncontact  optical pachymetry and Orbscan pachymetry // Cornea. — 2008. — Vol. 27, № 8. — P. 862- 865.
Crossref

4.Hashemi H., Roshani M., Mehravaran S. et al. Effect of corneal thickness on the agreement between ultrasound and Orbscan II pachymetry // J. Cataract Refract Surg. — 2007. — Vol. 33, № 10. — P. 1694- 1700.
Crossref

5.Lara F., Ferrfndez-SGnchez V., I^pez-Gil N. et al. Com-parison of partial coherence interferometry and ultrasound for anterior segment biometry // J. Cataract Refract Surg. — 2009. — Vol. 35, № 2. — P. 324-329.

6.Menassa N., Kaufmann C., Goggin M. et al. Comparison and reproducibility of corneal thickness and curvature readings obtained by the Galilei and the Orbscan II analysis systems // J. Cataract Refract Surg. — 2008. — Vol. 34, № 10. — P. 1742- 1747.
Crossref

7.Paul T., Lim M., Starr C. E. et al. Central corneal thickness measured by the Orbscan II system, contact ultrasound pachymetry and the Artemis 2 system // J. Cataract Refract Surg. — 2008. — Vol. 34, № 11. — P. 1906- 1912.
Crossref

8.Pillunat L. E., Kohlhaas M., Вцшп A. G. et al. Effect of corneal thickness on applanation tonometry, pneumotonometry and tonopen measurements // Springer-Verlag Berlin Heidelberg. — 2006. — Vol. Glaucoma. — P. 65- 72.
Crossref

9.Touboul D., Roberts C., Kiirautret J. et al. Correlations between corneal hysteresis, intraocular preassure and corneal central pachymetry // J. Cataract Refract Surg. — 2008. — Vol. 34, № 4. — P. 616-622.
Crossref

10.U3akhan Ц. Ц., Ilzkan M., Kanpolat A. Corneal thickness measurements in normal and keratoconic eyes: Pentacam comprehensive eye scanner versus noncontact specular mi-croscopy and ultrasound pachymetry // J. Cataract Refract Surg. — 2006. — Vol. 32, № 6. — P. 970-977.
Crossref