https://doi.org/10.31288/oftalmolzh201531823

Assessing the impact of cataract phacoemulsification at the level of intraocular pressure in patients with pseudoexfoliation syndrome

B. E. Malyugin, V. Agafonova, M. Z. Frankovska-Gerlak, V. S. Chubar

FGBI «IRTC» Eye Microsurgery «named. Acad. S. N. Fedorova of Russian Ministry of Health; Moscow, (Russia)

Material and methods. The study was conducted on 258 eyes of 138 patients with cataract and PEX. All patients with cataract and PEX were divided into three study groups: Group I with normal IOP before surgery; Group II with borderline IOP before surgery (IOP 22–27 mm Hg), Group III was comprised of patients with primary open angle glaucoma treated solely with anti-hypertensive drugs. Patients were followed up for 6 months. 

Results. Six months after cataract surgery the most pronounced hypotensive effect was observed in Group II and averaged 8.95 mm Hg (39.85 %) (p<0.05). In Group I and Group III the decrease in IOP was 5.16 (26.9 %) and 5.5 ( 28.67 %) respectively. 

Conclusion. In patients with cataract and PEX six months after surgery there was strong tendency for reduction of IOP post- surgery in all groups. The most pronounced hypotensive effect was observed in patients with cataract and PEX and borderline IOP prior to surgery, average IOP was 39.85 % (p<0.05).

Key words: phacoemulsification, intraocular pressure, pseudoexfoliation syndrome

References

Agafonova VV, Frankovska-Gerlak MZ, Chubar VS, Brizhak PE. Effect of cataract phacoemulsification on the level of intraocular pressure in the early postoperative period in patients with primary open-angle glaucoma in the background of pseudoexfoliative syndrome. Praktich med. 2013; (1–3): 23–7. In Russian.

Krol DS. Pseudoexfoliative syndrome and exfoliative glaucoma: author’s thesis for Doc. of Med. Sc. Kuibyshev. 1969. 

Malyugin BE. Medical-technological system of surgical rehabilitation of patients with cataracts by ultrasound phacoemulsification with intraocular lens implantation: author’s thesis for Doc. of Med. Sc. M.; 2002.

Nesterov AP. Glaukoma. M.: Glaukoma. M.: MIA; 2008. 360 p. 

Rasin OG, Savchenko AV, Litvinenko OA, Zhiviglazova EP. The hypotensive effect of cataract phacoemulsification in patients with decompensate primary open-angle glaucoma. Tavrich. Medico-biologich. Vestn. 2012. (2). 191–4.

Вuratto L. Cataract surgery — the transition from extracapsular cataract extraction to phacoemulsification. М.: Fabiano Editore; 1999. 474 p.

Fogagnolo P, Centofanti M, Figus M. Short-term changes in intraocular pressure after phacoemulsification in glaucoma patients. Ophthalmologica. 2012; 228 (3):154–8. 
Crossref

Guan H, Mick A, Porco T, Dolan BJ. Preoperative factors associated with IOP reduction after cataract surgery. Optom. Vis. Sci. 2013; 90(2):179–84. 
Crossref

Kim M, Park KH, Kim TW, Kim DM. Anterior chamber configuration changes after cataract surgery in eyes with glaucoma. Korean J. Ophthalmol. 2012; 26(2):97–103.
Crossref

Mansberger SL, Gordon MO, Jampel H et al. Ocular Hypertension Treatment Study Group. Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study. Ophthalmology. 2012;119 (9):1826–31.
Crossref

Mansberger SL, Gordon MO, Jampel H et al. Phacoemulsification and intraocular lens implantation in eyes with open-angle glaucoma. Acta Ophthalmol. Scand. 2001; 79 (3): 313–6.
Crossref

Poley BJ, Lindstrom RL, Samuelson TW, Schulze R. Jr. Intraocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes: evaluation of a causal relationship between the natural lens and open-angle glaucoma. J. Cataract Refract. Surg. 2009; 35(11):1946–51.

Rao A. Diurnal curve after phacoemulsification in patients with pseudoexfoliation syndrome and cataract. Semin. Ophthalmol. 2012;27 (2):1–5.

Sarda V, Rohart C, Fajnkuchen F et al. Pseudoexfoliation syndrome and phacoemulsification: comparative study with a control population./ J. Fr. Ophtalmol. 2010; 33(5): 319–326. 

Shingleton BJ, Heltzer J, O’Donoghue MW. Outcomes of phacoemulsification in patients with and without pseudoexfoliation syndrome. J. Cataract Refract. Surg. 2003;29 (6): 1080–1086.

Shingleton BJ, Nguyen BK, Eagan EF et al. Outcomes of phacoemulsification in fellow eyes of patients with unilateral pseudoexfoliation: single-surgeon series. J. Cataract Refract. Surg. 2008;34(2):274–279. 

Shingleton BJ, Laul A, Nagao K et al. Effect of phacoemulsification on intraocular pressure in eyes with pseudoexfoliation: single-surgeon series. J. Cataract Refract. Surg. 2008;34(11):1834–1841.

Sufi AR, Singh T, Mufti AA, Rather MH. Outcome of phacoemulsification in patients with and without pseudoexfoliation syndrome in Kashmir. BMC Ophthalmol. 2012;6:12–13.