J.ophthalmol.(Ukraine).2018;5:66-71.
https://doi.org/10.31288/oftalmolzh201856671
Received: 16 August 2018; Published on-line: 26 October 2018
Differential diagnosis of patients presenting with ocular and periorbital pain: a multidisciplinary approach
V.A. Vasyuta, Ophthalmologist, Dr Sc (Med); V.V. Biloshytsky, Neurosurgeon, Dr Sc (Med)
Romodanov Neurosurgery Institute, National Academy of Medical Science;
Kyiv (Ukraine)
E-mail: Vasyuta.v@ukr.net
TO CITE THIS ARTICLE: Vasyuta VA, Biloshytsky VV. Differential diagnosis of patients presenting with ocular and periorbital pain: a multidisciplinary approach. J.ophthalmol.(Ukraine).2018;5:66-71. https://doi.org/10.31288/oftalmolzh201856671
Ophthalmalgia (eye pain) is of interest to various fields of medicine, and may be due to ocular or extra-ocular causes. Common ocular causes include glaucoma, ocular inflammatory disease (like keratitis, skleritis or neuritis), and orbital disease. Notable extra-ocular causes include trigeminal neuralgia, headaches of various types, intracranial vascular lesions, and otolaryngological inflammatory disorders. The diagnosis and management of patients with ophthalmalgia requires a multidisciplinary approach with contributions from ophthalmology, neurology, neurosurgery, oto(rhino)neurology, as well as other specialties.
Keywords: eye pain, causes, multidisciplinary approach
References
- Lee AG, Brazis PW. The evaluation of eye pain with a normal ocular exam. Semin Ophthalmol. 2003 Dec;18(4):190–9.
Crossref - Ermolaev AP. [Causes of pain syndrome in terminal glaucoma]. Klinicheskaia gerontologiia. 2009; (10-11):68–71. Russian.
- Obermann M, Katsarava Z. Update on trigeminal neuralgia. Expert Rev Neurother. 2009;9(3):323–9.
Crossref - Colombo B, Dalla Libera D, Comi G. Ocular Pain: a neurological perspective. Neurol Sci. 2010 Jun;31 Suppl 1:S103–5.
Crossref - Nesterov AP. [Glaucoma]. Moscow: Meditsina; 1995. Russian.
- Berkoff DJ, Sanchez LD. An uncommon presentation of acute angle closure glaucoma. J Emerg Med. 2005 Jul;29(1):43–4.
Crossref - Leibowitz HM. The red eye. N Engl J Med. 2000;343:345–51.
Crossref - Pergolizzi J, Ahlbeck K, , Aldington D, et al. The development of chronic pain: physiological CHANGE necessitates a multidisciplinary approach to treatment. Curr Med Res Opi. 2013 Sep;29(9):1127–35.
Crossref - Geber C, Baumgärtner U, Schwab R, Muller H, Stoeter P, Dieterich M, et al. Revised definition of neuropathic pain and its grading system: an open case series illustrating its use in clinical practice. Am J Med. 2009 Oct;122(10 Suppl):S3–12.
Crossref - Reichling DB, Levine JD. Critical role of nociceptor plasticity in chronic pain. Trends Neurosci. 2009 Dec;32(12):611-8.
- Hayreh SS, Podhajsky PA, Zimmerman B. Ocular manifestations of giant cell arteritis. Am J Ophthalmol. 1998 Apr;125(4):509-20.
- Hirata H, Meng I. Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease. Invest Ophthalmol Vis Sci. 2010 Aug;51(8):3969-76.
- Tear fluid hyperosmolality increases nerve impulse activity of cold thermoreceptor endings of the cornea. Parra A, Gonzalez-Gonzalez O, Gallar J, Belmonte C. Pain. 2014 Aug;155(8):1481–91.
- Patel S, Alió JL, Artola A, Martinez MJ. Tear volume and stability after LASIK. J Refract Surg. 2007 Mar;23(3):290–8.
- Jabs DA, Mudun A, Dunn JP, Marsh MJ. Episcleritis and scleritis: clinical features and treatment results. Am J Ophthalmol. 2000;130:469–76.
- Okhravi N, Odufuwa B, McCluskey P. Scleritis. Surv Ophthalmol. 2005 Jul-Aug;50(4):351–63.
- Maggioni F, Ruffatti S, Viaro F, Mainardi F, Lisotto C, Zanchin G.. A case of posterior scleritis: differential diagnosis of ocular pain. J Headache Pain. 2007 Apr;8(2):123-6.
- The International Classification of Headache Disorders, 3rd edition. Headache Classification Committee of the International Headache Society (IHS). Cephalalgia. 2018 Jan; 38(1): 1-211.
- Arnold AC. Evolving management of optic neuritis and multiple sclerosis. Am J Ophthalmol. 2005;139:1101–8.
- Balcer LJ. Clinical practice. Optic neuritis. N Engl J Med. 2006 Mar 23;354(12):1273–80.
- Kupersmith MJ, Miller NR, Moke PS. Optic Neuritis Study Group: neurological impairment 10 years after optic neuritis. Arch Neurol. 2004 Sep;61(9):1386-9.
- Rodriguez M, Siva A, Cross SA, O'Brien PC, Kurland LT. Optic neuritis: a population-based study in Olmsted County, Minnesota. Neurology. 1995 Feb;45(2):244-50.
- Athappilly G, Pelak VS, Mandava N, Bennett JL. Ischemic optic neuropathy. Neurol Res. 2008 Oct;30(8):794–800.
- Gordon LK. Orbital inflammatory disease: a diagnostic and therapeutic challenge. Eye (Lond). 2006;20:1196–1206.
- Kurz PA., Suhler EB, Choi D, Rosenbaum JT. Rituximab for treatment of ocular inflammatory disease: a series of four cases. Br J Ophthalmol. 2009;93:546-8.
- Gladstone JP. An approach to the patient with painful ophthalmoplegia, with a focus on Tolosa–Hunt syndrome. Curr Pain Headache Rep. 2007 Aug;11(4):317–25. Review.
- Mombaerts I, Goldschmeding R, Schlingemann RO, Koornneef L. What is orbital pseudotumor? Surv Ophthalmol. 1996;41:66–78.
- Mombaerts I, Koornneef L. Current status in the treatment of orbital myositis. Ophthalmology. 1997;104:402–8.
- Scott IU, Siatkowski RM. Idiopathic orbital myositis. Curr Opin Rheumatol. 1997;9:504–12.
- Goadsby PJ, Cittadini E, Burns B, Cohen A.S. Trigeminal autonomic cephalalgias: diagnostic and therapeutic developments. Curr Opin Neurol. 2008 Jun;21(3):323–30.
- Evans RW, Pareja JA. Expert opinion: supraorbital neuralgia. Headache. 2009;49(2):278–81.
- Lipton RB, Bigal ME. Migraine: epidemiology, impact, and risk factors for progression. Headache. 2005 Apr;45 Suppl 1:S3-S13.
- Shindler KS, Sankar PS, Volpe NJ, Piltz-Seymour JR. Intermittent headaches as the presenting sign of subacute angle-closure glaucoma. Neurology. 2005;65:757-8.
- Levin M, Ward TN. Ophthalmoplegic migraine. Curr Pain Headache Rep. 2004 Aug;8(4):306-9.
- Manzouri B, Sainani A, Plant GT, et al. The aetiology and management of long-lasting sixth nerve palsy in ophthalmoplegic migraine. Cephalalgia. 2007 Mar;27(3):275-8.
- Prakash S, Patell R. Paroxysmal hemicrania: an update. Curr Pain Headache Rep. 2014;18(4):1–8.
- Robbins MS, Starling AJ, Pringsheim TM, Becker WJ, Schwedt TJ. Treatment of Cluster Headache: The American Headache Society Evidence-Based Guidelines. Headache. 2016;56:1093–106.
- Williams MH, Broadley SA. SUNCT and SUNA: clinical features and medical treatment. J Clin Neurosci. 2008;15:526–34.
- Prakash S, Patel P. Hemicrania continua: clinical review, diagnosis and management. J Pain Res. 2017;10:1493–509.
- Bartsch T, Goadsby P. Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input. Brain. 2002;125:1496–509.
- Smith WS, Messing RO. Cerebral aneurysm presenting as cough headache. Headache. 1993 Apr;33(4):203-4.
- Gorelick PB, Hier DB, Caplan LR, Langenberg P. Headache in acute cerebrovascular disease. Neurology. 1986 Nov;36(11):1445-50.
- Staikov IN, Mattle HP. Vertebrobasilar dolichoectasia and exertional headache. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1544.
- Hirata H, Oshinsky ML. Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels. J Neurophysiol. 2012 Feb;107(4):1199-209.