Oftalmol Zh. 2013; 5: 14-8.

https://doi.org/10.31288/oftalmolzh201351418

Morphometric features of retina in amblyopic and pair eye in children with amblyopia and hypermetropic refraction

Boichuk I. M., Yakhnitsa E. I.

SI « Institute of eye Diseases and Tissue therapy by V.P. Filatov, NAMS, Ukraine», Odessa «Center of Eye Microsurgery», Kiev

Purpose to study the peculiarities of central retina morphometric parameters in amblyopic and pair eye in children with amblyopia.

Material and methods 137 children (274 eyes) of 4—12 y. o. with an amblyopia and hypometropic refraction were examined, among them with the disbinocular amblyopia — 80 (56,6 %), with refractive amblyopia — 33 (24,8%) and with an isometropic amblyopia — 24 patients (18,8 %). Control group was 20 healthy children 6—8 y.o. The comparative description of retinal macular area morphometric parameters (macular volume, fovea thickness, thickness of retina in 1 MM, 3 MM and in 6 MM from the center of fovea in four sectors in amblyopic and pair eyes) was conducted applying standard protocols with the help of Stratus OCT model 3000. Results the greater volume of macula, thickness of fovea, are revealed, increased thickness of macular retina area in 1 mm and in 6 mm from the center of fovea mainly in a lower sector in amblyopic eyes as compared to a pair. Generally thickness of macular retina in segments was thicker in 3 mm in comparison to 6mm from a center in amblyopic as well as in the pair eye.

Conclusions The differences in morphometric parameters in central area of retina are established between amblyopic and pair eye that is confirmed by the greater thickness of fovea, of macula in 1 mm and in 6 mm from center in all segments. The large thickness of retina is set for certain in fovea and macula by scans (nasal, temporal, superior) on the amblyopic eye in comparison to pair eye. Generally thickness of macular retina in segments was thicker in 3 mm in comparison to 6mm from a center in amblyopic as well as in the pair eye.

Key words: amblyopia, optical coherent tomographyfl, morphometric parameters of central retina in amblyopic and pair eye.

References

1.Avetisov ES. Strabismic amblyopia and its treatment. M.: Meditsina; 1968. 208 p.

2.Avetisov SE, Kashchenko TP, Shamshinova AM. Visual functions and their correction in children. M.: Meditsina; 2005. 872 p.

3.Boichuk IM, Ivanitskaya EV. Results of application of optical coherence tomography of the retina and optic nerve in children with monolateral amblyopia. Current problems of medical and social rehabilitation of children with disabling ocular pathology: proceedings of III scientific-practical conference with international participation. Yevpatoria, 4-6 October 2006: 59- 60.

4.Boichuk IM, Ivanitskaya EV. The results of optical coher-ence tomography of the retina and optic nerve in children with high degree monolateral amblyopia. Oftalmol Zh. 3: 46-9.

5.Botabekova TK, Kurgambekova NS. Optical coherence to-mography in the diagnosis of amblyopia. Vestn Oftalmol. 2005; 121(5): 28-9.

6.Shamshinova AM, Yakovleva AA, Romanova EV. Clinical physiology of vision. M.: NMF MBH; 2002. 972 p.

7.Ivanitskaya EV. Optical coherence tomography in the diag-nosis of the state of the macular region of the retina. Oftalmol Zh. 2007; 5: 71-3.

8.Yoon SW, Park WH, Baek SN, Kong SM. Thickness of macular retinal layer and peripapillary retinal nerve fiber layer in patients with hyperopic anisometropic amblyopiaa. Korean J Ophthalmol. 2005; 19(1): 62-7.
Crossref

9.Lempert P. The Axial Length/Disc Area Ratio in Aniso-metropic Hyperopic Amlyopia: a hypothesis for decreased unilateral vision associated with hyperopic anisometropia. Ophthalmology. 2004; 111(2): 304-8.
Crossref

10.Leguire LE, Rogers GL, Bremer DL. Amblyopia: the nor-mal eye is not normal. J Pediatr Ophthalmol Strabismus. 1990; 27: 32-8.

11.Altintas O, Yuksel N, Ozkan B, Caglar Y. Thickness of the retinal nerve fiber layer, macular thickness, and macular volume in patients with strabismac amblyopia. J Pediatr Ophthalmol Strabismus. 2005; 42(4): 216-21.

12.Al-Haddad CE, El Mollayess GM, Cherfan CG, Jaafar DF, Bashshur ZF. Retinal nerve fiber layer and macular thickness in amblyopia as measured by spectral-domain optical coherence tomography. Br J Ophthalmol. 2011. Mar: 11.
Crossref

13.Kee SY, Lee SY, Lee YC Thicknesses of the fovea and reti-nal nerve fiber layer in amblyopic and normal eyes in children Korean J Ophthalmol. 2006; 20(3): 177- 81.
Crossref

14.Lim MC, Hoh ST, Foster PJ et al. Use of optical coherence tomography to asses variations in macular retinal thickness in myopia Invest Ophthalmol Vis Sci. 2005; 46(3): 974- 8.
Crossref

15.Liu H, Zhong L, Zhou X, Jin QZ. Macular Abnormality Observed by Optical Coherence Tomography in Children with Amblyopia Failing to Achieve Normal Visual Acuity After Long-Term Treatment J Pediatr Ophthalmol Strabis-mus. 2009; 2: 1-7.
Crossref

16.Mehmet Ersin Oba, Gokhan Gulkilik et al. The avalution of macular thickness in eyes with strabismic amblyopia XI th meeting of the ISA. 2010; 22- 25 Sep: 63.

17.Huynh SC, Samarawickrama C, Wang XY et al. Macular and nerve fiber layer thickness in amblyopia: the Sydney Childhood Eye Study. Ophthalmology. 2009; 116: 1604- 9.
Crossref

18.Park KA, Park DY, Oh SY. Analysis of spectral-domain optical coherence tomography measurements in amblyopia: a pilot study. Br J Ophthalmol. 2011. Mar: 22.
Crossref

19.Quoc EB, Delepine B, Tran TH. Thichness of retinal nerve fiber layer and macular volume in children and adults with strabismic and anisometropic amblyopia. J Fr Ophtalmol. 2009 Sep; 32(7): 488-95.

20.Paunescu LA, Shuman JS, Price LL, et al. Reproducibil-ity of nerve fiber thickness, macular thickness, and optic nerve head measurements using Stratus OCT. Invest Ophthalmolol Vis Sci. 2004; 1716-24.
Crossref

21.Son C Huynh, Chameen Samarawickrama, Xiu Ying Wang. Macular and Nerve Fiber Layer Thichness in Amblyopia. American Academy of Ophthalmology. 2009; 116: 1604- 9.
Crossref